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Regarding Omicron! Answers from the National Health Commission

发布时间:2021-12-03 点击量:3848

1.Discovery and prevalence of the Omicron variant

On November 9, 2021, South Africa detected a novel coronavirus B.1.1.529 variant from case samples. In just two weeks, this variant became the dominant variant among COVID - 19 infection cases in Gauteng Province, South Africa, showing a rapid growth. On November 26, the WHO designated it as the fifth "variant of concern" (VOC) and named it the Omicron variant after the Greek letter. As of November 28, the import of this variant had been monitored in South Africa, Israel, Belgium, Italy, the United Kingdom, Austria, and Hong Kong, China. No import of this variant has been found in other provinces and cities in China. The Omicron variant was first discovered and reported in South Africa, but this does not mean that the virus evolved and formed in South Africa. The place of discovery of the variant is not its origin.

2.Possible reasons for the emergence of the Omicron variant

According to the information currently shared in the GISAID database of the novel coronavirus, the number of mutation sites of the Omicron variant of the novel coronavirus is significantly higher than that of all novel coronavirus variants that have been prevalent in the past two years, especially with more mutations in the virus spike protein. The possible reasons for its emergence may be as follows:
(1) After an immunodeficient patient is infected with the novel coronavirus, a large number of mutations accumulate during a long - term evolution in the body, and it is transmitted through a chance opportunity.
(2) A certain animal population is infected with the novel coronavirus. During the process of the virus spreading among the animal population, it undergoes adaptive evolution, with a mutation rate higher than that in humans. Subsequently, it spills over and infects humans.

(3) This variant has been continuously prevalent for a long time in countries or regions with backward monitoring of the novel coronavirus genome variation. Due to insufficient monitoring capabilities, the intermediate generations of the evolving virus have not been detected in a timely manner.

3.Transmission ability of the Omicron variant

At present, there is no systematic research data on the transmission ability, pathogenicity, and immune escape ability of the Omicron variant. However, the Omicron variant has important amino - acid mutation sites in the spike protein of the previous four VOC variants, Alpha, Beta, Gamma, and Delta. These include mutation sites that enhance the affinity for cell receptors and the virus replication ability. Epidemiological and laboratory monitoring data show a surge in the number of cases infected with the Omicron variant in South Africa and its partial replacement of the Delta variant. Further monitoring and research on its transmission ability are needed.
Facing the newly - emerged Omicron variant of the novel coronavirus, what should the public pay attention to in daily life and work?
(1) Wearing masks remains an effective way to block the spread of the virus, and this also applies to the Omicron variant. Even if you have completed the full - course vaccination and received a booster shot, you still need to wear masks in indoor public places, public transportation, and other places. In addition, wash your hands frequently and ensure good indoor ventilation.
(2) Conduct personal health monitoring. When there are suspected COVID - 19 symptoms, such as fever, cough, shortness of breath, etc., monitor your body temperature in a timely manner and seek medical treatment actively.
(3) Reduce non - essential entry and exit. In just a few days, many countries and regions have successively reported the import of the Omicron variant. China also faces the risk of the import of this variant, and our understanding of this variant is still limited. Therefore, you should try to reduce travel to high - risk areas, strengthen personal protection during the journey, and reduce the chance of being infected with the Omicron variant.

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